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SCF induces γ-globin gene expression by regulating downstream transcription factor COUP-TFII

Increased fetal hemoglobin expression in adulthood is associated with acute stress erythropoiesis. However, the mechanisms underlying γ-globin induction during the rapid expansion of adult erythroid progenitor cells have not been fully elucidated. Here, we examined COUP-TFII as a potential repressor...

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Autori principali: Aerbajinai, Wulin, Zhu, Jianqiong, Kumkhaek, Chutima, Chin, Kyung, Rodgers, Griffin P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927201/
https://ncbi.nlm.nih.gov/pubmed/19401563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-170712
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