Potentiating Cancer Immunotherapy Using an Oncolytic Virus

Oncolytic viruses (OVs) are highly immunogenic and this limits their use in immune-competent hosts. Although immunosuppression may improve viral oncolysis, this gain is likely achieved at the cost of antitumoral immunity. We have developed a strategy wherein the immune response against the OV leads...

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Main Authors: Bridle, Byram W, Stephenson, Kyle B, Boudreau, Jeanette E, Koshy, Sandeep, Kazdhan, Natasha, Pullenayegum, Eleanor, Brunellière, Jérôme, Bramson, Jonathan L, Lichty, Brian D, Wan, Yonghong
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927075/
https://ncbi.nlm.nih.gov/pubmed/20551919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.98
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