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Recombinant Vesicular Stomatitis Virus Transduction of Dendritic Cells Enhances Their Ability to Prime Innate and Adaptive Antitumor Immunity

Dendritic cell (DC)–based vaccines are a promising strategy for tumor immunotherapy due to their ability to activate both antigen-specific T-cell immunity and innate immune effector components, including natural killer (NK) cells. However, the optimal mode of antigen delivery and DC activation remai...

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Hlavní autoři: Boudreau, Jeanette E, Bridle, Byram W, Stephenson, Kyle B, Jenkins, Kristina M, Brunellière, Jérôme, Bramson, Jonathan L, Lichty, Brian D, Wan, Yonghong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835245/
https://ncbi.nlm.nih.gov/pubmed/19401673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.95
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