Transient Demyelination Increases the Efficiency of Retrograde AAV Transduction

Adeno-associated virus (AAV) is capable of mediating retrograde viral transduction of central and peripheral neurons. This occurs at a relatively low efficiency, which we previously found to be dependent upon capsid serotype. We sought to augment retrograde transduction by providing increased axonal...

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Bibliografiske detaljer
Main Authors:	Hollis, Edmund R, Jamshidi, Pouya, Lorenzana, Ariana O, Lee, Jae K, Gray, Steven J, Samulski, Richard J, Zheng, Binhai, Tuszynski, Mark H
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2010
Fag:	Original Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2927074/ https://ncbi.nlm.nih.gov/pubmed/20502445 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.97
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Transient Demyelination Increases the Efficiency of Retrograde AAV Transduction

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