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Recognition of Virus Infection and Innate Host Responses to Viral Gene Therapy Vectors

The innate immune and inflammatory response represents one of the key stumbling blocks limiting the efficacy of viral-based therapies. Numerous human diseases could be corrected or ameliorated if viruses were harnessed to safely and effectively deliver therapeutic genes to diseased cells and tissues...

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Detalhes bibliográficos
Main Authors: Shayakhmetov, Dmitry M, Di Paolo, Nelson C, Mossman, Karen L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927067/
https://ncbi.nlm.nih.gov/pubmed/20551916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.124
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