Identification of Genetically Modified Maraba Virus as an Oncolytic Rhabdovirus

To expand our current array of safe and potent oncolytic viruses, we screened a variety of wild-type (WT) rhabdoviruses against a panel of tumor cell lines. Our screen identified a number of viruses with varying degrees of killing activity. Maraba virus was the most potent of these strains. We built...

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Detalhes bibliográficos
Main Authors: Brun, Jan, McManus, Dan, Lefebvre, Charles, Hu, Kang, Falls, Theresa, Atkins, Harold, Bell, John C, McCart, J. Andrea, Mahoney, Douglas, Stojdl, David F
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927055/
https://ncbi.nlm.nih.gov/pubmed/20551913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.103
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