Axolotl Nanog activity in mouse embryonic stem cells demonstrates that ground state pluripotency is conserved from urodele amphibians to mammals

Cells in the pluripotent ground state can give rise to somatic cells and germ cells, and the acquisition of pluripotency is dependent on the expression of Nanog. Pluripotency is conserved in the primitive ectoderm of embryos from mammals and urodele amphibians, and here we report the isolation of a...

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Dettagli Bibliografici
Autori principali: Dixon, James E., Allegrucci, Cinzia, Redwood, Catherine, Kump, Kevin, Bian, Yuhong, Chatfield, Jodie, Chen, Yi-Hsien, Sottile, Virginie, Voss, S. Randal, Alberio, Ramiro, Johnson, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2010
Soggetti:
Development and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926951/
https://ncbi.nlm.nih.gov/pubmed/20736286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.049262
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