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Determination of the γ-secretase inhibitor MK-0752 in human plasma by online extraction and electrospray tandem mass spectrometry (HTLC-ESI-MS/MS)

A sensitive and rapid HTLC-ESI-MS/MS method with an advanced online sample preparation was developed for determination of the γ-secretase inhibitor MK-0752 in human plasma using an internal standard. Plasma samples (100 μL) were diluted and injected directly onto an online extraction column (Cohesiv...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bai, Feng, Tagen, Michael, Colotta, Courtney, Miller, Laura, Fouladi, Maryam, Stewart, Clinton F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926936/
https://ncbi.nlm.nih.gov/pubmed/20702149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2010.07.019
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