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RNA polymerase mapping during stress responses reveals widespread nonproductive transcription in yeast

BACKGROUND: The use of genome-wide RNA abundance profiling by microarrays and deep sequencing has spurred a revolution in our understanding of transcriptional control. However, changes in mRNA abundance reflect the combined effect of changes in RNA production, processing, and degradation, and thus,...

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Autors principals: Kim, Tae Soo, Liu, Chih Long, Yassour, Moran, Holik, John, Friedman, Nir, Buratowski, Stephen, Rando, Oliver J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926786/
https://ncbi.nlm.nih.gov/pubmed/20637075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2010-11-7-r75
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