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Sequence-specific recognition of methylated DNA by human zinc-finger proteins

DNA methylation is an essential epigenetic mark. Three classes of mammalian proteins recognize methylated DNA: MBD proteins, SRA proteins and the zinc-finger proteins Kaiso, ZBTB4 and ZBTB38. The last three proteins can bind either methylated DNA or unmethylated consensus sequences; how this is achi...

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Bibliografske podrobnosti
Main Authors: Sasai, Nobuhiro, Nakao, Mitsuyoshi, Defossez, Pierre-Antoine
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926618/
https://ncbi.nlm.nih.gov/pubmed/20403812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq280
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