A bacterial antirepressor with SH3 domain topology mimics operator DNA in sequestering the repressor DNA recognition helix

Direct targeting of critical DNA-binding elements of a repressor by its cognate antirepressor is an effective means to sequester the repressor and remove a transcription initiation block. Structural descriptions for this, though often proposed for bacterial and phage repressor–antirepressor systems,...

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Autors principals: León, Esther, Navarro-Avilés, Gloria, Santiveri, Clara M., Flores-Flores, Cesar, Rico, Manuel, González, Carlos, Murillo, Francisco J., Elías-Arnanz, Montserrat, Jiménez, María Angeles, Padmanabhan, S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926617/
https://ncbi.nlm.nih.gov/pubmed/20410074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq277
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