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Genome-wide analysis of mRNA abundance in two life-cycle stages of Trypanosoma brucei and identification of splicing and polyadenylation sites

Transcription of protein-coding genes in trypanosomes is polycistronic and gene expression is primarily regulated by post-transcriptional mechanisms. Sequence motifs in the untranslated regions regulate mRNA trans-splicing and RNA stability, yet where UTRs begin and end is known for very few genes....

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Detalhes bibliográficos
Main Authors: Siegel, Tim Nicolai, Hekstra, Doeke R., Wang, Xuning, Dewell, Scott, Cross, George A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926603/
https://ncbi.nlm.nih.gov/pubmed/20385579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq237
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