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The catalytic function of the Rev1 dCMP transferase is required in a lesion-specific manner for translesion synthesis and base damage-induced mutagenesis

The Rev1-Polζ pathway is believed to be the major mechanism of translesion DNA synthesis and base damage-induced mutagenesis in eukaryotes. While it is widely believed that Rev1 plays a non-catalytic function in translesion synthesis, the role of its dCMP transferase activity remains uncertain. To d...

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書誌詳細
主要な著者: Zhou, Ying, Wang, Jillian, Zhang, Yanbin, Wang, Zhigang
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926598/
https://ncbi.nlm.nih.gov/pubmed/20388628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq225
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