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Genome-wide approaches to systematically identify substrates of the ubiquitin/proteasome pathway
The ubiquitin/proteasome system handles the majority of controlled proteolysis in eukaryotes. Defects in the ubiquitin/proteasome system have been implicated in diseases ranging from cancers to neurodegenerative disorders. However, the precise role of ubiquitin/proteasome-mediated degradation in hea...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2926183/ https://ncbi.nlm.nih.gov/pubmed/20637515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2010.06.003 |
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