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Genome-wide approaches to systematically identify substrates of the ubiquitin/proteasome pathway

The ubiquitin/proteasome system handles the majority of controlled proteolysis in eukaryotes. Defects in the ubiquitin/proteasome system have been implicated in diseases ranging from cancers to neurodegenerative disorders. However, the precise role of ubiquitin/proteasome-mediated degradation in hea...

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Detalhes bibliográficos
Main Authors: Liu, Chang, Choe, Vitnary, Rao, Hai
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926183/
https://ncbi.nlm.nih.gov/pubmed/20637515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibtech.2010.06.003
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