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Vaccination with HPV16 L2E6E7 fusion protein in GPI-0100 adjuvant elicits protective humoral and cell-mediated immunity

A vaccine comprising human papillomavirus type 16 (HPV16) L2, E6 and E7 in a single tandem fusion protein (termed TA-CIN) has the potential advantages of both broad cross-protection against HPV transmission through induction of L2 antibodies able to cross neutralize different HPV types and of therap...

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Detalhes bibliográficos
Main Authors: Karanam, Balasubramanyam, Gambhira, Ratish, Peng, Shiwen, Jagu, Subhashini, Kim, Dae-Jin, Ketner, Gary W., Stern, Peter L., Adams, Robert J., Roden, Richard B.S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925461/
https://ncbi.nlm.nih.gov/pubmed/19095032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.11.099
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