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Influence of XRCC1 Genetic Polymorphisms on Ionizing Radiation-Induced DNA Damage and Repair

It is well known that ionizing radiation (IR) can damage DNA through a direct action, producing single- and double-strand breaks on DNA double helix, as well as an indirect effect by generating oxygen reactive species in the cells. Mammals have evolved several and distinct DNA repair pathways in ord...

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Detalhes bibliográficos
Main Authors: Sterpone, Silvia, Cozzi, Renata
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925273/
https://ncbi.nlm.nih.gov/pubmed/20798883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/780369
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