Hepsin Cooperates with Myc in the Progression of Adenocarcinoma in a Prostate Cancer Mouse Model

BACKGROUND: Hepsin is a cell surface protease that is over-expressed in more than 90% of human prostate cancer cases. The previously developed Probasin-hepsin/Large Probasin-T antigen (PB-hepsin/LPB-Tag) bigenic mouse model of prostate cancer demonstrates that hepsin promotes primary tumors that are...

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Main Authors: Nandana, Srinivas, Ellwood-Yen, Katharine, Sawyers, Charles, Wills, Marcia, Weidow, Brandy, Case, Thomas, Vasioukhin, Valeri, Matusik, Robert
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925264/
https://ncbi.nlm.nih.gov/pubmed/19938013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21093
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