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Diurnal regulation of MTP and plasma triglyceride by CLOCK is mediated by SHP
We examined the role of clock genes in the diurnal regulation of plasma triglyceride-rich apolipoprotein B-lipoproteins and their biosynthetic chaperone, microsomal triglyceride transfer protein (MTP). Clock (mt/mt) mice showed sustained hypertriglyceridemia and high MTP expression. CLOCK knockdown...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925198/ https://ncbi.nlm.nih.gov/pubmed/20674862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2010.05.014 |
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