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Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure
Brain edema in acute liver failure (ALF) remains lethal. The role of vasogenic mechanisms of brain edema has not been explored. We previously demonstrated that matrix metalloproteinase-9 (MMP-9) contributes to the pathogenesis of brain edema. Here, we show that MMP-9 mediates disruptions in tight ju...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925168/ https://ncbi.nlm.nih.gov/pubmed/19821483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23203 |
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