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Matrix Metalloproteinase-2 in the Development of Diabetic Retinopathy and Mitochondrial Dysfunction

In the pathogenesis of diabetic retinopathy, retinal mitochondria become dysfunctional resulting in accelerated apoptosis of its capillary cells. Matrix metalloproteinases2 (MMP2) is considered critical in the cell integrity and cell survival, and diabetes activates MMP2 in the retina and its capill...

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Autors principals: Mohammad, Ghulam, Kowluru, Renu A.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925063/
https://ncbi.nlm.nih.gov/pubmed/20479714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2010.89
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