Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation

Histone deacetylase (HDAC) inhibitors increase histone acetylation and enhance both memory and synaptic plasticity. The current model for the action of HDAC inhibitors assumes that they alter gene expression globally and thus affect memory processes in a nonspecific manner. Here, we show that the en...

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Detalhes bibliográficos
Main Authors: Vecsey, Christopher G., Hawk, Joshua D., Lattal, K. Matthew, Stein, Joel M., Fabian, Sara A., Attner, Michelle A., Cabrera, Sara M., McDonough, Conor B., Brindle, Paul K., Abel, Ted, Wood, Marcelo A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925045/
https://ncbi.nlm.nih.gov/pubmed/17553985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0296-07.2007
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