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Histone Deacetylase Inhibitors Enhance Memory and Synaptic Plasticity via CREB: CBP-Dependent Transcriptional Activation

Histone deacetylase (HDAC) inhibitors increase histone acetylation and enhance both memory and synaptic plasticity. The current model for the action of HDAC inhibitors assumes that they alter gene expression globally and thus affect memory processes in a nonspecific manner. Here, we show that the en...

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Библиографические подробности
Главные авторы: Vecsey, Christopher G., Hawk, Joshua D., Lattal, K. Matthew, Stein, Joel M., Fabian, Sara A., Attner, Michelle A., Cabrera, Sara M., McDonough, Conor B., Brindle, Paul K., Abel, Ted, Wood, Marcelo A.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925045/
https://ncbi.nlm.nih.gov/pubmed/17553985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0296-07.2007
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