Inhibition of ABCG2-Mediated Drug Efflux by Naphthopyrones from Marine Crinoids

Five new naphthopyrones (1-5) along with the known compounds TMC-256A1, 5,8-dihydroxy-6-methoxy-2-propyl-4H-naphtho[2,3-b]pyran-4-one, TMC-256C1, comaparvin, 6-methoxy comaparvin, and 6-methoxycomaparvin 5-methyl ether (7-11) were isolated from crinoids of the family Comasteridae. All compounds were...

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Bibliographic Details
Main Authors: Bokesch, Heidi R., Cartner, Laura K., Fuller, Richard W., Wilson, Jennifer A., Henrich, Curtis J., Kelley, James A., Gustafson, Kirk R., McMahon, James B., McKee, Tawnya C.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924950/
https://ncbi.nlm.nih.gov/pubmed/20627559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.05.057
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