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FMN binding site of yeast NADPH-cytochrome P450 reductase exposed at the surface is highly specific

NADPH-cytochrome P450 reductase (CPR) transfers two reducing equivalents derived from NADPH via FAD and FMN to microsomal P450 monooxygenases in one-electron transfer steps. The crystal structure of yeast CPR (yCPR) contains a surface-exposed FMN binding site (FMN2 site) at the interface of the FMN...

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Bibliografiske detaljer
Main Authors: Ivanov, Alexis S., Gnedenko, Oksana V., Molnar, Andrey A., Archakov, Alexander I., Podust, Larissa M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924936/
https://ncbi.nlm.nih.gov/pubmed/20557022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100055v
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