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Short-lived neutral FMN and FAD semiquinones are transient intermediates in cryo-reduced yeast NADPH-cytochrome P450 reductase

The electron configuration of flavin cofactors, FMN and FAD, is a critical factor governing the reactivity of NADPH-cytochrome P450 reductase (CPR). The current view of electron transfer by the mammalian CPR, based on equilibrium redox potentials of the flavin cofactors, is that the two electron-red...

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Bibliografiske detaljer
Udgivet i:Arch Biochem Biophys
Main Authors: Davydov, Roman M., Jennings, Gareth, Hoffman, Brian M., Podust, Larissa M.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7575000/
https://ncbi.nlm.nih.gov/pubmed/31445894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2019.108080
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