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Expression of Human Frataxin Is Regulated by Transcription Factors SRF and TFAP2
BACKGROUND: Friedreich ataxia is an autosomal recessive neurodegenerative disease caused by reduced expression levels of the frataxin gene (FXN) due to expansion of triplet nucleotide GAA repeats in the first intron of FXN. Augmentation of frataxin expression levels in affected Friedreich ataxia pat...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924884/ https://ncbi.nlm.nih.gov/pubmed/20808827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012286 |
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