Fine mapping of the hereditary haemorrhagic telangiectasia (HHT)3 locus on chromosome 5 excludes VE-Cadherin-2, Sprouty4 and other interval genes

BACKGROUND: There is significant interest in new loci for the inherited condition hereditary haemorrhagic telangiectasia (HHT) because the known disease genes encode proteins involved in vascular transforming growth factor (TGF)-β signalling pathways, and the disease phenotype appears to be unmasked...

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Main Authors: Govani, Fatima S, Shovlin, Claire L
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924844/
https://ncbi.nlm.nih.gov/pubmed/20701797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2040-2384-2-15
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