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Enantiomerically Pure trans-β-Lactams from α-Amino Acids via Compact Fluorescent Light (CFL) Continuous Flow Photolysis

Photolysis of α-diazo N-methoxy-N-methyl (Weinreb) β-ketoamides derived from enantiomerically pure (EP) α-amino acids affords the corresponding EP β-lactam via an intramolecular Wolff rearrangement. Photochemistry is promoted with either standard UV irradiation or through the use of a 100W compact f...

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Detalhes bibliográficos
Main Authors: Mimieux Vaske, Yvette S., Mahoney, Maximillian E., Konopelski, Joseph P., Rogow, David L., McDonald, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924779/
https://ncbi.nlm.nih.gov/pubmed/20698705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1050023
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