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B cell-targeted therapies in autoimmunity: rationale and progress

B cells are recognized as main actors in the autoimmune process. Autoreactive B cells can arise in the bone marrow or in the periphery and, if not properly inhibited or eliminated, can lead to autoimmune diseases through several mechanisms: autoantibody production and immune complex formation, cytok...

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Detalhes bibliográficos
Main Authors: Fiorina, Paolo, Sayegh, Mohamed H
Formato: Artigo
Idioma:Inglês
Publicado em: Biology Reports Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924700/
https://ncbi.nlm.nih.gov/pubmed/20948646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B1-39
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