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Identification and Characterization of the Carbohydrate Ligands Recognized by Pertussis Toxin through Glycan Microarray and Surface Plasmon Resonance

Binding of pertussis toxin (PTx) was examined by glycan microarray; 53 positive hits fell into four general groups. One group represents sialylated bi-antennary compounds with an N-glycan core terminating in α2-6 linked sialic acid. The second group consists of multi-antennary compounds with a canon...

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Bibliografiske detaljer
Main Authors: Millen, Scott H., Lewallen, Daniel M., Herr, Andrew B., Iyer, Suri S., Weiss, Alison A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924675/
https://ncbi.nlm.nih.gov/pubmed/20515023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi100474z
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