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Spinophilin directs Protein Phosphatase 1 specificity by blocking substrate binding sites
The serine/threonine Protein Phosphatase 1 (PP1) dephosphorylates hundreds of key biological targets. PP1 associates with ≥200 regulatory proteins to form highly specific holoenzymes. These regulatory proteins target PP1 to its point of action within the cell and prime its enzymatic specificity for...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924587/ https://ncbi.nlm.nih.gov/pubmed/20305656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1786 |
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