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T cells as therapeutic targets in SLE

T cells contribute to the initiation and perpetuation of autoimmunity in systemic lupus erythematosus (SLE), and seem to be directly involved in the development of related organ pathology. Defects associated with CD8(+) and T-regulatory (T(REG)) cell function manifest in parallel with the expanded C...

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Autori principali: Crispín, José C., Kyttaris, Vasileios C., Terhorst, Cox, Tsokos, George C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924434/
https://ncbi.nlm.nih.gov/pubmed/20458333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2010.60
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