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Up-regulation of p21 and TNF-α is mediated in lycorine-induced death of HL-60 cells

BACKGROUND: Leukemia is one of the most life-threatening cancers today, and acute promyelogenous leukemia (APL) is a common type of leukemia. Many natural compounds have already been found to exhibit significant anti-tumor effects. Lycorine, a natural alkaloid extracted from Amaryllidaceae, exhibite...

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Detalhes bibliográficos
Main Authors: Liu, Jing, Hu, Ji-liang, Shi, Bi-Wei, He, Yan, Hu, Wei-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924328/
https://ncbi.nlm.nih.gov/pubmed/20682078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-10-25
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