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Functional analysis of dicer-2 missense mutations in the siRNA pathway of Drosophila
The Drosophila RNase III enzyme Dicer-2 processes double-stranded RNA (dsRNA) precursors into small interfering RNAs (siRNAs). It also interacts with the siRNA product and R2D2 protein to facilitate the assembly of an RNA-induced silencing complex (RISC) that mediates RNA interference. Here, we char...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924196/ https://ncbi.nlm.nih.gov/pubmed/18454937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.04.118 |
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