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Loqs and R2D2 act sequentially in the siRNA pathway in Drosophila

In Drosophila melanogaster, the small interfering RNA (siRNA) pathway is triggered by exogenous double-stranded RNA (dsRNA) or upon viral infection. This pathway requires Dicer-2 (Dcr-2) in association with a dsRNA binding protein (dsRBP) called R2D2. A potentially distinct siRNA pathway, which requ...

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Hlavní autoři: Marques, Joao Trindade, Kim, Kevin, Wu, Pei-Hsuan, Alleyne, Trevis M., Jafari, Nadereh, Carthew, Richard W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919300/
https://ncbi.nlm.nih.gov/pubmed/20037596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1735
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