Propylthiouracil inhibits the conversion of l-thyroxine to l-triiodothyronine
6-n-propylthiouracil (PTU) administered to male Sprague-Dawley rats maintained on 2 and 5 μg L-thyroxine (T(4))/100 g body weight resulted in a marked reduction in the rate of conversion of L-thyroxine to L-triiodothyronine (T(3)). These effects could not be ascribed to induced hypothyroidism since...
Guardat en:
| Publicat a: | J Clin Invest |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
1972
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4639029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107063 |
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