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Role of Nod2 in the development of Crohn’s disease
Crohn’s Disease (CD) is caused by a loss of the regulatory capacity of the immune apparatus. Nod2 is an intracellular bacterial sensor and its mutations are associated with the development of CD. Here we summarize recent and controversial findings about the role of the Nod2 mutants in the disease pr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924159/ https://ncbi.nlm.nih.gov/pubmed/19573617 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2009.06.005 |
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