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Reactive Oxygen Species and Hyaluronidase 2 Regulate Airway Epithelial Hyaluronan Fragmentation

Hyaluronidase 2 (Hyal2) is a hyaluronan (HA)-degrading enzyme found intracellularly or/and anchored to the plasma membrane through glycosylphosphatidylinositol (GPI). Normal human bronchial epithelial cells (NHBE) grown at the air-liquid interphase (ALI), treated with PI-specific phospholipase C (PI...

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Autori principali: Monzon, Maria E., Fregien, Nevis, Schmid, Nathalie, Falcon, Nieves S., Campos, Michael, Casalino-Matsuda, S. Marina, Forteza, Rosanna Malbran
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924017/
https://ncbi.nlm.nih.gov/pubmed/20554532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135194
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