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Hyaluronan Fragments/CD44 Mediate Oxidative Stress–Induced MUC5B Up-Regulation in Airway Epithelium

Mucus hypersecretion with elevated MUC5B mucin production is a pathologic feature in many airway diseases associated with oxidative stress. In the present work, we evaluated MUC5B expression in airways and in primary cultures of normal human bronchial epithelial (NHBE) cells, as well as the mechanis...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Casalino-Matsuda, S. Marina, Monzon, Maria E., Day, Anthony J., Forteza, Rosanna M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Thoracic Society 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645525/
https://ncbi.nlm.nih.gov/pubmed/18757307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0073OC
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