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Hyaluronan Fragments/CD44 Mediate Oxidative Stress–Induced MUC5B Up-Regulation in Airway Epithelium

Mucus hypersecretion with elevated MUC5B mucin production is a pathologic feature in many airway diseases associated with oxidative stress. In the present work, we evaluated MUC5B expression in airways and in primary cultures of normal human bronchial epithelial (NHBE) cells, as well as the mechanis...

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Hlavní autoři: Casalino-Matsuda, S. Marina, Monzon, Maria E., Day, Anthony J., Forteza, Rosanna M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2645525/
https://ncbi.nlm.nih.gov/pubmed/18757307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0073OC
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