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Phosphorylation and Ubiquitination of Degron Proximal Residues Are Essential for Class II Transactivator (CIITA) Transactivation and Major Histocompatibility Class II Expression

Major histocompatibility (MHC) class II molecules are cell surface glycoproteins that present extracellular antigens to CD4(+) T cells and are essential for initiation of the adaptive immune response. MHC class II expression requires recruitment of a master regulator, the class II transactivator (CI...

詳細記述

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書誌詳細
主要な著者: Bhat, Kavita Purnanda, Truax, Agnieszka Dorota, Greer, Susanna Fletcher
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923977/
https://ncbi.nlm.nih.gov/pubmed/20538595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127746
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