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D-Amino Acid Oxidase Generates Agonists of the Aryl Hydrocarbon Receptor from D-Tryptophan

The aryl hydrocarbon receptor (AHR) is well known for its role in mediating the toxic and adaptive responses to xenobiotic compounds. Recent studies also indicate that AHR ligands are endogenously produced and may be essential for normal development. Previously, we showed that the endogenous enzyme,...

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Detalhes bibliográficos
Main Authors: Nguyen, Linh P., Hsu, Erin L., Chowdhury, Goutam, Dostalek, Miroslav, Guengerich, F. Peter, Bradfield, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923838/
https://ncbi.nlm.nih.gov/pubmed/19860415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900043s
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