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Spinal α2-adrenoceptor mediated analgesia in neuropathic pain reflects brain derived nerve growth factor and changes in spinal cholinergic neuronal function
INTRODUCTION: Spinal α2-adrenoceptor stimulation produces analgesia in neuropathic pain states, and this effect in animals is blocked by inhibitors of brain derived neurotrophic factor (BDNF) function. In rats, α2-adrenoceptor stimulation normally inhibits acetylcholine release, but excites release...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923834/ https://ncbi.nlm.nih.gov/pubmed/20613480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3181de6d2c |
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