Genetic Analyses of the Chimeric CYP11B1/CYP11B2 Gene in a Korean Family with Glucocorticoid-Remediable Aldosteronism

Glucocorticoid-remediable aldosteronism (GRA) is an autosomal-dominant inheritable form of hyperaldosteronism with early onset hypertension. GRA is caused by unequal crossing-over of the steroid 11β-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) genes. As a result of chimeric gene duplicat...

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Autors principals: Lee, Ihn Suk, Kim, Seul Young, Jang, Hye Won, Kim, Min Kyeong, Lee, Ju Hee, Lee, Yun Hyeong, Jo, Young Suk
Format: Artigo
Idioma:Inglês
Publicat: The Korean Academy of Medical Sciences 2010
Matèries:
Case Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923798/
https://ncbi.nlm.nih.gov/pubmed/20808686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2010.25.9.1379
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