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Targeting HSV-1 virions for specific binding to epidermal growth factor receptor-vIII bearing tumor cells
Oncolytic herpes simplex virus (HSV) vectors have been used in early phase human clinical trials as a therapy for recurrent malignant glioblastoma. This treatment proved safe but limited improvements in patient survival were observed. The potency of these vectors might be enhanced by targeting vecto...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923688/ https://ncbi.nlm.nih.gov/pubmed/20508670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2010.22 |
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