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Functional Coexpression of HSV-1 Thymidine Kinase and Green Fluorescent Protein: Implications for Noninvasive Imaging of Transgene Expression

Current gene therapy technology is limited by the paucity of methodology for determining the location and magnitude of therapeutic transgene expression in vivo. We describe and validate a paradigm for monitoring therapeutic transgene expression by noninvasive imaging of the herpes simplex virus type...

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Detalhes bibliográficos
Main Authors: Jacobs, Andreas, Dubrovin, Michael, Hewett, Jeff, Sena-Esteves, Miguel, Tan, Cui-Wen, Slack, Mark, Sadelain, Michele, Breakefield, Xandra O, Tjuvajev, Juri G
Formato: Artigo
Idioma:Inglês
Publicado em: Stockton Press 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508134/
https://ncbi.nlm.nih.gov/pubmed/10933050
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