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ER Stress Controls Iron Metabolism Through Induction of Hepcidin
Hepcidin is a peptide hormone that is secreted by the liver and controls body iron homeostasis. Hepcidin overproduction causes anemia of inflammation, whereas its deficiency leads to hemochromatosis. Inflammation and iron are known extracellular stimuli for hepcidin expression. We found that endopla...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923557/ https://ncbi.nlm.nih.gov/pubmed/19679815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1176639 |
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