Safety and Immunogenicity of HCV E1E2 Vaccine Adjuvanted with MF59 Administered to Healthy Adults

BACKGROUND: Hepatitis C virus (HCV) causes chronic liver disease that often leads to cirrhosis and hepatocellular carcinoma. In animal studies, chimpanzees were protected against chronic infection following experimental challenge with either homologous or heterologous HCV genotype 1a strains which p...

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Autors principals: Frey, Sharon E., Houghton, Michael, Coates, Stephen, Abrignani, Sergio, Chien, David, Rosa, Domenico, Pileri, Piero, Ray, Ranjit, Di Bisceglie, Adrian, Rinella, Paola, Hill, Heather, Wolff, Mark C., Schultze, Viola, Han, Jang H., Scharschmidt, Bruce, Belshe, Robert B.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923449/
https://ncbi.nlm.nih.gov/pubmed/20619382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.06.084
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