Safety and Immunogenicity of HCV E1E2 Vaccine Adjuvanted with MF59 Administered to Healthy Adults

BACKGROUND: Hepatitis C virus (HCV) causes chronic liver disease that often leads to cirrhosis and hepatocellular carcinoma. In animal studies, chimpanzees were protected against chronic infection following experimental challenge with either homologous or heterologous HCV genotype 1a strains which p...

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Main Authors: Frey, Sharon E., Houghton, Michael, Coates, Stephen, Abrignani, Sergio, Chien, David, Rosa, Domenico, Pileri, Piero, Ray, Ranjit, Di Bisceglie, Adrian, Rinella, Paola, Hill, Heather, Wolff, Mark C., Schultze, Viola, Han, Jang H., Scharschmidt, Bruce, Belshe, Robert B.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923449/
https://ncbi.nlm.nih.gov/pubmed/20619382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2010.06.084
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