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Klotho: a novel phosphaturic substance acting as an autocrine enzyme in the renal proximal tubule

Klotho has profound effects on phosphate metabolism, but the mechanisms of how Klotho affects phosphate homeostasis is unknown. We detected Klotho in the proximal tubule cell, brush border, and urinary lumen, where phosphate homeostasis resides. Increasing Klotho in the kidney and urine chronically...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Hu, Ming Chang, Shi, Mingjun, Zhang, Jianning, Pastor, Johanne, Nakatani, Teruyo, Lanske, Beate, Razzaque, M. Shawkat, Rosenblatt, Kevin P., Baum, Michel G., Kuro-o, Makoto, Moe, Orson W.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Federation of American Societies for Experimental Biology 2010
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923354/
https://ncbi.nlm.nih.gov/pubmed/20466874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-154765
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