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Na/Bicarbonate Cotransporter NBCn1 in the Kidney Medullary Thick Ascending Limb Cell Line is Upregulated under Acidic Conditions and Enhances Ammonium Transport

In this study, we examined the effect of bicarbonate transporters on ammonium/ammonia uptake in the medullary thick ascending limb cell line ST-1. Cells were treated with 1 mM ouabain and 0.2 mM bumetanide to minimize carrier-mediated NH(4)(+) transport, and the intracellular accumulation of (14)C-m...

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Detalhes bibliográficos
Main Authors: Lee, Soojung, Lee, Hye Jeong, Yang, Han Soo, Thornell, Ian M., Bevensee, Mark O., Choi, Inyeong
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923243/
https://ncbi.nlm.nih.gov/pubmed/20591978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/expphysiol.2010.053967
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